Mpox Vaccine: A Comprehensive Overview
Introduction
Mpox (previously known as monkeypox) is a zoonotic viral infection caused by the monkeypox virus (MPXV). It is characterized by a rash that can progress through several stages, as well as symptoms such as fever, headache, muscle aches, and swollen lymph nodes.
JYNNEOS Vaccine
JYNNEOS is a 2-dose vaccine that has been developed to protect against MPXV infection. It is a modified vaccinia Ankara (MVA) vaccine, which means it uses a weakened form of the vaccinia virus to induce an immune response.
Efficacy
The JYNNEOS vaccine has been shown to be effective in preventing mpox disease. Studies have found that the vaccine is 85% effective in preventing symptomatic mpox infection and 100% effective in preventing severe mpox disease.
Side Effects
The most common side effects of the JYNNEOS vaccine include injection site pain, redness, and swelling. Other side effects that may occur include fever, chills, headache, muscle aches, and nausea. These side effects are typically mild and resolve within a few days.
Dosing
The JYNNEOS vaccine is given as a 2-dose series. The first dose is given intramuscularly, and the second dose is given 28 days later.
Who Should Get Vaccinated?
The JYNNEOS vaccine is recommended for people who are at high risk of mpox infection. This includes people who have been in close contact with someone who has mpox, people who travel to areas where mpox is common, and people who have certain medical conditions that make them more susceptible to infection.
Other Vaccines for Mpox
In addition to the JYNNEOS vaccine, there is one other vaccine that has been approved for the prevention of mpox. This vaccine is called ACAM2000, and it is a live attenuated vaccine that contains the vaccinia virus.
ACAM2000
ACAM2000 is a less effective vaccine than JYNNEOS, and it has more side effects. It is also not recommended for people who have certain medical conditions, such as a weakened immune system or eczema.
Conclusion
The JYNNEOS vaccine is a safe and effective way to prevent mpox infection. It is recommended for people who are at high risk of infection. If you are at high risk of infection, talk to your doctor about getting vaccinated.
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